HIV is the etiological agent of acquired immunodeficiency syndrome (AIDS). The virion is surrounded by a lipid envelope derived from the membrane of the host cell. Several viral glycoproteins are on the envelope. Each virus contains two copies of genomic RNAs of positive meaning. HIV 1 has been isolated from AIDS patients and a complex related to AIDS, and healthy people with high potential risk of developing AIDS. HIV 2 has been isolated from West African AIDS patients and asymptomatic HIV-positive individuals. HIV 1 and HIV 2 generate an immune response. The detection of anti-HIV antibodies in serum, plasma is the most efficient and common way to determine if a person has been exposed to HIV and to screen blood and blood products for HIV. Despite differences in their biological characteristics, their serological activities and genomic sequences, HIV 1 and HIV 2 show strong antigenic cross-reactivity. Most positive sera for HIV 2 can be identified using tests. The HIV 1.2 rapid test cassette (total blood / serum / plasma) is a quick test for qualitatively detecting the presence of anti-HIV 1 and / or HIV 2 antibody in a sample of total blood, serum or plasma. . The test uses a latex conjugate and several recombinant HIV proteins to selectively detect anti-HIV antibodies 1.2 in total blood, serum or plasma.